Modulation of insulin/IGFs pathways by sirtuin-7 inhibition in drug-induced chemoreistance
نویسندگان
چکیده
منابع مشابه
Modulation of insulin/IGFs pathways by sirtuin-7 inhibition in drug-induced chemoreistance
BACKGROUND Insulin and insulin-like growth factors (IGFs) are key regulators of metabolism and growth. Recent evidences suggest a key role of these pathways in non-classical tissues and the metabolic pathways by which these hormones exert their effects in neoplasia is unclear. AIMS To study insulin/IGFs pathways in drug sensitive and resistant cancer cells representing breast cancer (MCF-7), ...
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ژورنال
عنوان ژورنال: Diagnostic Pathology
سال: 2014
ISSN: 1746-1596
DOI: 10.1186/1746-1596-9-94